Investigators have uncovered how resistance to chemotherapies may occur in some cancers. Researchers focused on a pathway that harnesses reactive oxygen species (ROS) to kill cancer cells. The study found that mutations to VPS35, a key player in this pathway, can prevent chemotherapy-induced cell death. These results could help pinpoint treatment-resistant tumors.
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Discrimination-related depression, anxiety pronounced among multiracial, White, Asian populations
A new study found that over half of US adults experienced some form of discrimination, and individuals with high exposure to discrimination have more than five times the chances of screening positive for depression, and five times the chances of screening positive for anxiety. Compared to adults who do not experience discrimination, adults who do experience this mistreatment have nearly nine times the odds of screening positive for both depression and anxiety.
New approach could treat anthrax beyond the ‘point of no return’
Researchers show that a cocktail of growth factors reversed would-be lethal cell damage in mice with anthrax, suggesting that this approach could be adapted for use in patients.
AI meets oncology: New model personalizes bladder cancer treatment
Leveraging the power of AI and machine learning technologies, researchers developed a more effective model for predicting how patients with muscle-invasive bladder cancer will respond to chemotherapy. The model harnesses whole-slide tumor imaging data and gene expression analyses in a way that outperforms previous models using a single data type.
A genetic tree as a movie: Moving beyond the still portrait of ancestry
Researchers have created a way to see your family tree as a movie rather than a still portrait by tracing where your ancestors moved across the globe over time. The statistical method can also be used to model disease spread and studying how animals move through geographic regions.
Melting ice, more rain drive Southern Ocean cooling
Researchers found increased meltwater and rain explain 60% of a decades-long mismatch between predicted and observed temperatures in the ocean around Antarctica.
Long COVID patients feel pressure to prove their illness is real, study finds
People living with Long COVID often feel dismissed, disbelieved and unsupported by their healthcare providers, according to a new study.
We must not ignore eugenics in our genetics curriculum, says professor
To encourage scientists to speak up when people misuse science to serve political agendas, biology professor Mark Peifer of the University of North Carolina at Chapel Hill argues that eugenics should be included in college genetics curriculums.
Earliest days of Earth’s formation
New research sheds light on the earliest days of the earth’s formation and potentially calls into question some earlier assumptions in planetary science about the early years of rocky planets. Establishing a direct link between the Earth’s interior dynamics occurring within the first 100 million years of its history and its present-day structure, the work is one of the first in the field to combine fluid mechanics with chemistry to better understand the Earth’s early evolution.
A cleaner future for tires: Scientists pioneer chemical process to repurpose rubber waste
Every year, millions of tires end up in landfills, creating an environmental crisis with far-reaching consequences. In the United States alone, over 274 million tires were scrapped in 2021, with nearly a fifth of them being discarded into landfills. A study has now pioneered a technique for breaking down this rubber waste and transforming it into valuable precursors for epoxy resins. This technique offers an innovative and sustainable alternative to traditional recycling methods while significantly reducing rubber waste in landfills.