Human thermoregulation limits are lower than previously thought, indicating that some regions may soon experience heat and humidity levels exceeding safe limits for survival. The study underscores the urgent need to address climate change impacts on human health, providing vital data to inform public health strategies and climate models.
ScienceDaily
Clinical trial unearths hidden hypertension with automated searches of health records
A trial of 648 patients found that the new automated method and intervention strategy resulted in nearly four times as many diagnoses and treatment plans for high blood pressure compared with traditional office-based health care visits.
Discovery of Quina technology challenges view of ancient human development in East Asia
Researchers have uncovered a complete Quina technological system in the Longtan site in southwest China. The discovery challenges the widely held perception that the Middle Paleolithic period was mostly static in East Asia.
New AI models possible game-changers within protein science and healthcare
Researchers have developed new AI models that can vastly improve accuracy and discovery within protein science. Potentially, the models will assist the medical sciences in overcoming present challenges within, e.g. personalised medicine, drug discovery, and diagnostics.
Delicate balancing act determines how many genome gateways form in cells
As warehouses go, nuclei are more like libraries than bank vaults. Too many cellular components need access to the genome to lock it down like Fort Knox. Instead, large groupings of more than 1,000 individual protein molecules called nuclear pore complexes (NPCs) pepper the dividing membrane, serving as gateways for materials and messages entering and exiting the nucleus. While the basic need for this shuttle service is constant, scientists have shown that cells dynamically adjust their amounts of NPCs like a retail store opening more or fewer checkout lines throughout the day. Scientists now reveal the results of screening the entire human genome to find factors influencing how many NPCs are assembled.
Change in oxygen standards for trauma patients?
A recent study finds most critically injured patients can recover with less supplemental oxygen than has previously been suggested.
Martian dust could pose health risks to future astronauts
Inhaling dust particles from the Red Planet over long periods of time could put humans at risk of developing respiratory issues, thyroid disease and other health problems.
Researchers identify mutations that can lead to resistance to some chemotherapies
Investigators have uncovered how resistance to chemotherapies may occur in some cancers. Researchers focused on a pathway that harnesses reactive oxygen species (ROS) to kill cancer cells. The study found that mutations to VPS35, a key player in this pathway, can prevent chemotherapy-induced cell death. These results could help pinpoint treatment-resistant tumors.
Discrimination-related depression, anxiety pronounced among multiracial, White, Asian populations
A new study found that over half of US adults experienced some form of discrimination, and individuals with high exposure to discrimination have more than five times the chances of screening positive for depression, and five times the chances of screening positive for anxiety. Compared to adults who do not experience discrimination, adults who do experience this mistreatment have nearly nine times the odds of screening positive for both depression and anxiety.
New approach could treat anthrax beyond the ‘point of no return’
Researchers show that a cocktail of growth factors reversed would-be lethal cell damage in mice with anthrax, suggesting that this approach could be adapted for use in patients.